Vitamin C Side Effects

Serious Side Effects

Even though it seems like a harmless nutrient, vitamin C can cause serious side effects, especially if too much is taken. These side effects, which should be reported to your healthcare provider, include:
 
  • A blood clot in the legs (deep vein thrombosis, or DVT)
  • Kidney stones
  • Erosion of the teeth (seen with long-term use of chewable vitamin C tablets)
  • Worsening of sickle cell disease
  • Hemolysis (destruction of red blood cells) in people with glucose 6-phosphate dehydrogenase deficiency
  • Increased aluminum absorption into the body (which can be especially dangerous for people with kidney disease)
  • Signs of an allergic reaction, such as:
 
    • An unexplained rash
    • Itching
    • Hives
    • Swelling of the mouth or throat
    • Wheezing
    • Difficulty breathing.
 

Final Thoughts

If you think you are experiencing a side effect of vitamin C, please let your healthcare provider know. Also, let him or her know if you develop something that "just does not seem right." While it may not be a side effect, your healthcare provider will be able to diagnose and treat the problem.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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