When medications such as calcium channel blockers or clonidine are taken together with Tenormin, drug interactions may occur. While some interactions can result in decreased absorption of Tenormin into your blood, others may cause side effects such as low blood pressure, dizziness, or fainting. Some other medications that can lead to potential Tenormin drug interactions include reserpine, indomethacin, antacids containing calcium, and certain diabetes medicines.