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Ranexa and Pregnancy

As a pregnancy Category C medication, Ranexa (ranolazine) may not be safe for pregnant women. Although adequate research has not been done in pregnant women, the medication has been shown to cause delayed bone hardening and defects of the sternum when given to pregnant animals. However, there may be situations when the benefits of using the drug outweigh the possible risks to the unborn child.

Can Pregnant Women Take Ranexa?

Ranexa® (ranolazine) is a prescription medication used for the treatment of chronic angina (chest pain). At this time, it is unknown if Ranexa is safe for use during pregnancy.
 

What Is Pregnancy Category C?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Ranexa is classified as a pregnancy Category C medication.
 
Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause fetal harm in animal studies. Also, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 
When given to pregnant rabbits and rats, Ranexa increased the risk of delayed bone hardening and defects of the sternum. Ranexa has not been adequately studied in pregnant women.
 
It is important to note, however, that animals do not always respond to medicines in the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if her healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
 

Final Thoughts

If you are pregnant or thinking about becoming pregnant, let your healthcare provider know before taking Ranexa. He or she will consider both the benefits and risks before making a recommendation in your particular situation.
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Ranexa Medication Information

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