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Propafenone Side Effects

Common Side Effects

Propafenone has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking the drug were documented and (in some studies) compared to those that occurred in a similar group of people taking a placebo (a "sugar pill" that does not contain any active ingredients). As a result, it was possible to see what side effects occurred, how often they appeared, and how they compared to the placebo.
In these studies, the most common propafenone side effects included:
  • An unusual taste, such as a metallic taste in the mouth -- in up to 23 percent of people
  • Dizziness -- up to 15 percent
  • Nausea and vomiting -- up to 11 percent
  • Constipation -- up to 8 percent
  • Headache -- up to 6 percent
  • Fatigue -- up to 6 percent
  • Blurred vision -- up to 6 percent
  • Dry mouth -- up to 6 percent
  • Diarrhea -- up to 6 percent.
Other common reactions, occurring in 1 percent to 5 percent of people, included:
  • Weakness
  • Shortness of breath
  • Chest pain
  • Heartburn or indigestion
  • Heart rhythm problems
  • Heart failure
  • Rash
  • Fainting
  • Loss of appetite
  • Abdominal (stomach) pain and cramps
  • Loss of muscle coordination
  • Insomnia
  • A slow heart rate
  • Anxiety
  • Fever
  • Ringing in the ears
  • Difficulty swallowing
  • Gas
  • Tremor
  • Swelling of the arms, hands, legs, ankles, or feet
  • Sweating
  • Drowsiness
  • Low blood pressure (hypotension)
  • Joint pain.

Final Thoughts

You may experience some or none of the propafenone side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking propafenone or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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Propafenone Drug Information

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