Procardia Drug Interactions (Cont.)

 
Nefazodone (Serzone)
Nefazodone can increase the level of Procardia in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Procardia dose.
 
Protease Inhibitors
Protease inhibitors can increase the level of Procardia in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Procardia dose.
 
Quinidine
Procardia can decrease the level of quinidine in your blood, perhaps making it less effective. Also, quinidine may increase the level of Procardia in your blood, increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications.
 
Rifamycin Derivatives
Rifamycin derivatives can greatly reduce the level of Procardia in your blood, making it much less effective. It is generally not recommended to combine Procardia with rifamycin derivatives.
 
Certain Seizure Medications
Taking Procardia with certain seizure medications can decrease the level of Procardia in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of Procardia.
 
St. John's Wort
St. John's wort can decrease the level of Procardia in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of Procardia.
 
Tacrolimus (Prograf)
Procardia can increase the level of tacrolimus in your blood, increasing your risk of side effects. Your healthcare provider should monitor the level of tacrolimus in your blood and may need to decrease your tacrolimus dosage.
 
Warfarin (Coumadin, Jantoven)
There have been reports of an interaction between warfarin and Procardia. Procardia may increase your risk of bleeding while you are taking warfarin. Your healthcare provider may need to monitor you more closely, especially when starting or stopping Procardia.
 
(Procardia Drug Interactions Continued: Page 4)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;