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Nitroglycerin Spray

What If I Overdose on This Medicine?

An overdose with nitroglycerin spray can be dangerous. If you or someone else may have used too much, seek immediate medical attention.
(Click Nitrolingual Overdose or NitroMist Overdose for more information.)

How Does Nitroglycerin Spray Work?

Nitroglycerin spray works by relaxing the veins and arteries of the body. With the arteries and veins relaxed, the heart does not need to work so hard and does not require as much oxygen. Because angina is usually caused when there is not enough oxygen to meet the heart's needs, nitroglycerin spray can help to relieve angina attacks.

When and How to Use It

Some general considerations to keep in mind during treatment with nitroglycerin spray include the following:
  • This medication comes in the form of a liquid that is sprayed on or under the tongue.
  • You can use up to three sprays within 15 minutes. If your chest pain isn't relieved after one spray, try another. If chest pain continues after a third spray, you should seek immediate medical attention.
  • Nitroglycerin spray can also be used 5 to 10 minutes before activity that is anticipated to cause chest pain.
  • Do not shake the bottle. The first time you use each bottle (and if you have not used it for quite a while) you must prime it. Refer to the instructions that came with your prescription for details about priming the bottle.
  • Do not rinse or spit for 5 to 10 minutes after using the spray.
  • For nitroglycerin spray to work properly, it must be used as prescribed.
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Nitroglycerin Spray Information

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