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Drug Interactions With Nitroglycerin Spray

If certain medicines or substances are taken in combination with nitroglycerin spray, negative drug interactions could occur. Some of these reactions can decrease the effectiveness of the drugs or increase your risk for complications like low blood pressure. Ergot medicines, alcohol, and blood pressure medications are among the substances that can react with nitroglycerin spray.

An Overview of Nitroglycerin Spray Interactions

Nitroglycerin spray (Nitrolingual®, NitroMist®) may react with a number of other medications. Some of the drugs that can lead to interactions with nitroglycerin spray include but are not limited to:
    • Bromocriptine (Parlodel®)
    • Dihydroergotamine (Migranal®)
    • Ergonovine
    • Ergotamine (Cafergot®, Ergomar®)
    • Methylergonovine (Methergine®)
    • Pergolide (Permax®)
  • Phosphodiesterase type-5 (PDE5) inhibitors, such as:



Drug Interactions With Nitroglycerin Spray Explained

The following sections explain in detail the potentially negative interactions that can occur when nitroglycerin spray is combined with any of the drugs listed above.
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Nitroglycerin Spray Information

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