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Nitro-Dur Drug Interactions

Nitro-Dur Drug Interactions Explained

The following sections explain in detail the potentially negative reactions that can occur when Nitro-Dur is combined with any of the drugs listed above.
Combining alcohol with Nitro-Dur may increase the risk for low blood pressure (hypotension). Check with your healthcare provider before drinking alcohol while using Nitro-Dur.
Based on reports of a drug interaction with intravenous (IV) nitroglycerin, it is possible that Nitro-Dur could decrease the level of alteplase in the bloodstream, perhaps making it less effective. In the event that you need alteplase (which is sometimes used for people who are having a heart attack, blood clots, or certain types of strokes), make sure your healthcare provider knows you have been using Nitro-Dur.
Calcium Channel Blockers
Combining Nitro-Dur with certain calcium channel blockers may cause dangerously low blood pressure. Your blood pressure may need to be closely monitored if you take these medications together.
Ergot Medications
Ergot medications can make Nitro-Dur less effective at preventing chest pain (angina), and Nitro-Dur may increase the level of ergot medications in the blood, increasing the risk for ergot side effects. In general, this combination of medications should be avoided if possible.
Phosphodiesterase Type-5 (PDE5) Inhibitors
If you are using Nitro-Dur, you cannot take a PDE5 inhibitor, as dangerously low blood pressure may result.
One study has suggested that people taking rosiglitazone with a nitrate, including Nitro-Dur, might have an increased risk for poor blood flow to the heart, which may lead to a heart attack.
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Nitro-Dur Medication Information

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