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Mexiletine Dosage

What Is the Loading Dose?

If your healthcare provider determines that your arrhythmia needs to be controlled very quickly, you may be given an initial one-time dose of mexiletine 400 mg. This is called a loading dose. Eight hours later, you will begin the usual dosing schedule of 200 mg every eight hours. Your healthcare provider may choose to adjust the amount from there.

General Information on Taking Mexiletine

Some considerations to keep in mind during treatment with mexiletine include the following:
  • This medication comes in capsule form. It is usually taken by mouth every 8 hours, although some people may only need to take it every 12 hours.
  • You will begin taking mexiletine in a hospital setting, where you can be closely monitored.
  • Mexiletine should be taken with food or an antacid to help minimize stomach irritation.
  • Try to take your doses at about the same times each day to keep an even level of the drug in your bloodstream.
  • For the medication to work properly, it must be taken as prescribed. Do not stop taking it, even if you feel well, as your irregular heartbeat may return.
  • If you are unsure about anything related to your dosage or mexiletine dosing in general, please talk with your healthcare provider or pharmacist.
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Mexiletine Drug Information

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