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Drug Interactions With Mexiletine

Etravirine
Etravirine may decrease blood levels of mexiletine, potentially making it less effective. Your healthcare provider will need to closely monitor you to make sure mexiletine is adequately controlling your condition if you take it with etravirine.
 
Fosphenytoin
Fosphenytoin may decrease blood levels of mexiletine, which could make the medication less effective. Your healthcare provider may choose to monitor your mexiletine blood levels with a simple blood test if you take these medications together.
 
Phenytoin
Phenytoin may decrease blood levels of mexiletine, possibly making the medication less effective. Your healthcare provider may choose to monitor your mexiletine blood levels with a simple blood test if you take these medications together.
 
Theophylline
Mexiletine can increase theophylline blood levels, which could increase the risk for theophylline toxicity. If you take theophylline, your healthcare provider will need to monitor your blood level and will likely adjust your dosage when you start, stop, or have a change in your mexiletine dosage.
 

Final Thoughts

It is possible that not all mexiletine drug interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific interactions that may apply to you.
 
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Mexiletine Drug Information

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