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Uses for Metoprolol

This medication has been licensed to treat a number of conditions. The uses for the immediate-release form include:
Uses for the extended-release form include treatment for:
Metoprolol does not cure high blood pressure, angina, or congestive heart failure, however.
The medication may also be recommended "off-label" for other reasons, such as treatment for migraines or anxiety. Metoprolol has not been licensed for use in children, although it is often used to treat specific conditions in children.
(Click What Is Metoprolol Used For? for more information, including possible off-label uses.)

How Does It Work?

Metoprolol is part of a class of drugs called beta-adrenergic blocking agents, or beta blockers for short. As the name implies, these drugs block beta receptors, which are located in a number of places within the body, including the heart and blood vessels. These receptors are what stress hormones (such as adrenaline) attach to, causing certain reactions in the body. These reactions can include increases in:
  • Heart rate
  • The force with which the heart pumps blood
  • Blood pressure (both systolic and diastolic).
Metoprolol helps to block a specific type of beta receptor called beta-1 receptors. By blocking them, the medication causes the reverse effect of these stress hormones. It decreases heart rate and both systolic and diastolic blood pressure, as well as the workload of the heart. This means that the heart requires less blood and oxygen to work properly.
Metoprolol is a beta-1 selective (or cardioselective) beta blocker. This means that it mostly blocks beta-1 receptors, especially at normal doses. However, it can block beta-2 receptors in the lungs to some extent, especially at higher dosages. This can lead to breathing problems, especially in people with asthma or similar conditions.
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Metoprolol Drug Information

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