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Metoprolol Dosing
There are several possible dosages of metoprolol; the one your healthcare provider recommends will depend on the medical condition being treated and your age, among other things. For the treatment of high blood pressure with immediate-release metoprolol, dosing recommendations generally start at 100 mg once a day or 50 mg twice a day. With extended-release metoprolol, the recommended starting dosage is 25 mg to 100 mg once daily.
The dose of metoprolol (Lopressor®, Toprol-XL®) your healthcare provider recommends will vary, depending on a number of factors, including:
- Your age
- The form of metoprolol (immediate-release or extended-release)
- The medical condition being treated
- Other medical conditions you may have
- Other medications you may be currently taking
- How you respond to metoprolol.
The recommended starting dose of immediate-release metoprolol tartrate (Lopressor) for people with high blood pressure is 100 mg once a day or 50 mg twice a day. With extended-release metoprolol succinate (Toprol-XL), the recommended starting dosage is 25 mg to 100 mg once a day. After a week or longer, based on the blood pressure response and/or metoprolol side effects, the metoprolol dosage may be increased or decreased. Your healthcare provider may also add a diuretic (a "water pill") or another blood pressure medication if your condition is not controlled by metoprolol alone.
The maximum recommended daily dose of immediate-release metoprolol for this use is 450 mg, and the maximum daily dosage of extended-release metoprolol is 400 mg.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD



