Drug Interactions With Metoprolol

Not all medicines respond well when taken together, and there is always the possibility of developing negative drug interactions. With metoprolol, these interactions can cause your body to metabolize the medicines differently than intended and result in: excessive drug levels in your system, extremely low blood pressure, slow heart rate, or low blood sugar levels, among other things. Medications that may potentially lead to drug interactions with metoprolol include calcium channel blockers, certain diabetes medicines, and nonsteroidal anti-inflammatory drugs.

 

Metoprolol Drug Interactions: An Introduction

 Metoprolol (available as Lopressor® and Toprol-XL®) has a number of other medicines that it can potentially interact with. Some of these drug interactions with metoprolol can include:
 
  • Digoxin (Digitek®, Lanoxicaps®, Lanoxin®)
o Verapamil (Calan®, Isoptin®)
o Verapamil Extended-Release (Calan® SR, Covera-HS®, Isoptin® SR, Verelan®, Verelan®-PM)
o Diltiazem ER (Cardizem® CD, Cardizem® LA, Cardizem® SR, Dilacor XR®, Diltia XT®, Tiazac®)
o Nifedipine ER (Adalat® CC, Procardia XL®)
(Drug Interactions With Metoprolol Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;