Heart Disease Home > Side Effects of Trandolapril

Common side effects of trandolapril can include dizziness, extremely low blood pressure, and heartburn or indigestion, among other things. Some rare trandolapril side effects include insomnia, anxiety, constipation, and erectile dysfunction (also known as ED or impotence). Among the side effects with trandolapril that you should report immediately to your healthcare provider are itching, wheezing, unexplained blisters or peeling of the skin, and stomach pain with or without vomiting.

Side Effects of Trandolapril: An Overview

As with any medicine, there are possible side effects with trandolapril (Mavik®). However, not everyone who takes the medicine will experience side effects. In fact, most people tolerate trandolapril well. When people do develop trandolapril side effects, in many cases they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects can occur but are less common.
About 1.4 percent of people stop taking trandolapril because of side effects.
(The trandolapril side effects discussed below are not a complete list of side effects reported with trandolapril. Your healthcare provider can discuss a more complete list of side effects with you.)

Common Trandolapril Side Effects

Trandolapril has been studied extensively in clinical trials, with thousands of people worldwide having been evaluated. In these studies, side effects are always documented and compared to those that occur in a similar group of people not taking the medicine. Based on these studies, the most common trandolapril side effects seen in people with high blood pressure include:
  • Cough -- up to 2 percent (see Mavik Cough)
  • Dizziness -- up to 1.3 percent
  • Diarrhea -- up to 1 percent.
For people with left ventricular dysfunction or congestive heart failure, the most common side effects with trandolapril include:
  • Cough -- up to 35 percent
  • Dizziness -- up to 23 percent
  • Extremely low blood pressure -- up to 11 percent
  • Heartburn or indigestion (dyspepsia) -- up to 6.4 percent.
Other side effects with trandolapril (occurring in more than 1 percent of people with high blood pressure, left ventricular dysfunction, or congestive heart failure) include but are not limited to:
  • Increased potassium levels in the blood
  • Fainting (syncope)
  • Slowed heart rate
  • A stroke
  • Weakness.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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