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Tiazac Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Tiazac is combined with any of the drugs listed above.
 
Benzodiazepines
Tiazac can increase the level of certain benzodiazepines in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your benzodiazepine dose to prevent this interaction from occurring.
 
Beta Blockers
Combining Tiazac with a beta blocker may increase your risk of side effects, especially low blood pressure (hypotension) and a slow heart rate (bradycardia). Your healthcare provider should closely monitor your heart rate and blood pressure if you are taking a beta blocker with Tiazac.
 
Buspirone (BuSpar)
Tiazac can increase the level of buspirone in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your buspirone dosage to prevent this.
 
Carbamazepine (Tegretol, Tegretol XR)
Tiazac can increase the level of carbamazepine in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your carbamazepine dosage to prevent this interaction from occurring.
 
Cimetidine (Tagamet)
Cimetidine may increase the level of Tiazac in your blood, potentially increasing your risk of Tiazac side effects. Your healthcare provider may need to adjust your Tiazac dosage or may suggest an alternative to cimetidine.
 
Clonidine (Catapres, Catapres-TTS, Duraclon)
Combining Tiazac with clonidine can increase the risk of a dangerously slow heart rate. If you must take these two medications together, your healthcare provider should monitor your heart rate closely.
  
Cyclosporine (Gengraf, Neoral, Sandimmune)
Tiazac may increase the level of cyclosporine in your blood, possibly increasing your risk of side effects. Your healthcare provider should monitor your cyclosporine levels and may need to adjust your dosage if you are taking both of these medications.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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