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Side effects may occur with the use of Tiazac, and depression appears to be one of them (occurring in less than 2 percent of people taking the drug). However, because depression is so common within the general population, it is difficult to determine with certainty if there is actually a link between Tiazac and depression symptoms.

Tiazac and Depression: An Overview

Tiazac® (diltiazem hydrochloride) is a prescription medication known as a calcium channel blocker. It is used to treat high blood pressure (hypertension) and chest pain (known medically as angina).
Just like any other medicine, Tiazac side effects are possible. One of these potential side effects is depression.

Tiazac and Depression: How Common Is It?

The safety and effectiveness of diltiazem (the active ingredient of Tiazac) has been extensively studied in clinical trials. In these trials, less than 2 percent of people reported depression as a side effect of the medication.
The challenge with Tiazac and depression is that given how uncommon depression is reported with diltiazem products and how common it is within the general population, it is difficult to tell whether the depression is caused by Tiazac alone or other factors.

Tiazac and Depression: Final Thoughts

For people taking Tiazac, depression may occur. Therefore, if you notice any possible symptoms of depression while taking the drug, or if something "just does not seem right," you should talk to your healthcare provider. He or she will be able to diagnose and treat the problem. If your healthcare provider believes the medicine may be causing your symptoms, he or she may recommend another angina or blood pressure medicine.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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