Heart Disease Home > Nitrostat Uses

Adults who experience episodes of chest pain (angina) associated with coronary artery disease may benefit from Nitrostat. This prescription medicine can help relieve angina attacks or prevent anticipated episodes of chest pain from occurring. It works by relaxing the veins and arteries in the body to improve blood and oxygen supply to the heart. There are currently no "off-label" uses for Nitrostat.

What Is Nitrostat Used For?

Nitrostat® (nitroglycerin tablets) is a prescription drug approved for treating attacks of angina pectoris associated with coronary artery disease. This means that this drug is approved to relieve episodes of chest pain caused by coronary artery disease (also known as coronary heart disease), a condition in which the small blood vessels that supply oxygen to the heart become too narrow to adequately supply the heart with enough blood and oxygen.
Nitrostat is also approved for use just before activities that will likely result in chest pain. Typically, these activities involve physical exertion, such as exercise or sexual intercourse.
This angina medicine is used by dissolving the tablets under the tongue or between the gums and cheek. If your chest pain does not subside after taking 3 tablets within 15 minutes (5 minutes apart), it is time to seek immediate medical attention, as you may be having a heart attack.
Nitrostat does not work long enough to prevent future angina attacks. If you find that you are having frequent attacks, talk with your healthcare provider about a longer-acting form of nitroglycerin or another form of treatment that is more appropriate for such situations.

How Does Nitrostat Work?

Nitrostat works by relaxing the veins and arteries in the body. With the arteries and veins relaxed, the heart does not need to work so hard and does not require as much oxygen. Because angina is usually caused when there is not enough oxygen to meet the heart's needs, the use of Nitrostat can help relieve angina attacks.
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Last reviewed by: Kristi Monson, PharmD;
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