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At this time, it is unknown if Nitrostat® (nitroglycerin tablets) passes through breast milk. Therefore, if you are breastfeeding or plan to start, you should talk with your healthcare provider before using Nitrostat. The manufacturer recommends that women use this drug with caution while breastfeeding.
No research has been done to see if Nitrostat passes through breast milk. This lack of research likely reflects the fact that Nitrostat is approved to treat chest pain (angina) due to coronary artery disease, a condition that is quite rare in young women.
Based on the known actions and side effects of Nitrostat, if the drug does pass through breast milk, it is reasonable to expect that it could cause low blood pressure (hypotension) and headaches in the infant.
Nitroglycerin ointment (Nitro-Bid®, Rectiv™) is sometimes used to treat anal fissures. In one study of 40 breastfeeding women who used nitroglycerin ointment to treat anal fissures, no problems were seen in the babies. It is unclear if Nitrostat would be similarly safe.
You should discuss breastfeeding and Nitrostat use with your healthcare provider. Each woman's situation is different, and you and your healthcare provider understand your situation best. After considering what you want and expect, as well as your current health situation, the two of you can make a shared decision that is right for you.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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