Heart Disease Home > Mexiletine

Available by prescription only, mexiletine is used to control the heart rhythm in people who have a potentially life-threatening ventricular arrhythmia. Possible side effects include lightheadedness and shakiness, among others. This medicine is only available as a generic and comes as a capsule that is taken every 8 or 12 hours. It works by slowing down electrical signals in the heart, helping to stabilize the heart rhythm.

What Is Mexiletine?

Mexiletine (Mexitil®) is a prescription medication approved to treat certain types of irregular heart rhythms (arrhythmias). This drug is specifically designed to treat life-threatening irregular heartbeats known as ventricular arrhythmias. It belongs to a class of medications called antiarrhythmics.
(Click What Is Mexiletine Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, mexiletine can cause side effects. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
Common side effects seen with mexiletine include but are not limited to:
  • Gastrointestinal (GI) side effects
  • Lightheadedness
  • Shakiness (tremors).
(Click Mexiletine Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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