Heart Disease Home > Coreg CR

Coreg CR is a prescription drug used for treating certain conditions related to the heart and blood vessels, such as heart failure or high blood pressure. It comes in capsule form and is typically taken once a day. The medication is a beta blocker that works by blocking beta receptors in the body, an action that decreases blood pressure and the workload on the heart.

What Is Coreg CR?

Coreg CR® (carvedilol CR) is a prescription medicine that has been licensed to treat several conditions related to the heart and blood vessels. It is part of a part of a class of drugs called beta blockers. It is a long-acting medication that is taken just once a day.
(Click Coreg CR Uses for more information, including possible off-label uses.)

Who Makes This Medication?

Coreg CR is made by GlaxoSmithKline.

How Does Coreg CR Work?

Coreg CR is part of a class of drugs called beta-adrenergic blocking agents, or beta blockers for short. As the name implies, beta blockers block beta receptors in the body. Beta receptors are located in a number of places, including the heart and blood vessels. These receptors are what stress hormones (such as adrenaline) attach to and cause certain reactions in the body, such as an increase in:
By blocking beta receptors, it causes the reverse effect of stress hormones. It decreases heart rate and both systolic and diastolic blood pressures, as well as the workload on the heart. This means that the heart requires less blood and oxygen to work properly. The medication also increases the efficiency of the heart, allowing more blood to be pumped out to the rest of the body.
Unlike a lot of other beta blockers, Coreg CR also blocks alpha receptors. The alpha blocker component of the drug works more on the peripheral blood vessels (arteries in the arms and legs). By blocking the alpha receptors, it relaxes these blood vessels.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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