Mitochondria are important structures found in almost all human cells. They are known as organelles ("little organs"). Mitochondria have several extremely important roles, including energy production and influence over cell growth and cell death. There are several known mitochondrial diseases. Some of these diseases are genetic, while others are not. These diseases are relatively rare, but they can have devastating effects, such as seizures, strokes, heart problems, and developmental problems. Studies have shown that CoQ10 supplementation can help improve the brain symptoms, such as seizures, in people with certain mitochondrial diseases. For this use, the benefit is slow to develop, often taking several months to see improvement.
Benefits of CoQ10 for Heart Health
Studies have shown that CoQ10 supplements may improve many of the symptoms of congestive heart failure (CHF) when used in combination with the usual CHF medications. However, this issue is controversial; some studies have not shown any benefit of CoQ10 in terms of several important measures of CHF, including how well the heart pumps blood. Currently, the American Heart Association and the American College of Cardiology do not recommend CoQ10 for treating congestive heart failure.
Some studies have also shown that CoQ10 may help with chest pain (known medically as angina). However, there is not really enough evidence to recommended CoQ10 for this use at this time.
Written by/reviewed by: Kristi Monson, PharmD;Arthur Schoenstadt, MD
Last reviewed by: KristiMonson, PharmD;
List of references (click here):
Jellin JM, editor. Pharmacist's Letter/Prescriber's Letter Natural Medicines Comprehensive Database Web site. Available at: http://naturaldatabase.com/. Accessed January 22, 2008.
Radford MJ, et al. American College of Cardiology; American Heart Association Task Force on Clinical Data Standards; American College of Chest Physicians; International Society for Heart and Lung Transplantation; Heart Failure Society of America. ACC/AHA key data elements and definitions for measuring the clinical management and outcomes of patients with chronic heart failure. Circulation 2005;112(12):1888-916.
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