Amiodarone premixed injection belongs to a group of medications known as antiarrhythmics. Most antiarrhythmic medications are further categorized using a system known as the Vaughn-Williams classification system. This system divides the medications into four general classes based on how they work.
Amiodarone premixed injection is considered a Class III antiarrhythmic; however, it has properties of all four classes and therefore works in several different ways. The most important way it works is by its Class III antiarrhythmic actions.
Class III antiarrhythmic medications block potassium channels in the heart, preventing potassium from leaving the cells of the heart muscle. This action prolongs the heart's refractory period, which is the period of time heart cells will not respond to a new electrical signal. By extending the refractory period, amiodarone premixed injection helps the heart tissue resist any electrical signal that is trying to come through prematurely.
Can Children Use Amiodarone Premixed Injection?
Amiodarone premixed injection has not been shown to be safe or effective in children, and is not approved for use in this age group. Talk to your child's healthcare provider about the risks and benefits of using this medicine in children.
Is It Safe for Older Adults?
There were not enough older adults in clinical studies to determine whether older adults will respond to this medication any differently than younger age groups. Because older adults are more likely to have other medical conditions that may increase their risk for certain amiodarone premixed injection side effects, they may need to be started on lower doses and monitored more carefully.
What About Off-Label Uses?
On occasion, your healthcare provider may recommend this medication for treating something other than the conditions discussed in this article. This is called an "off-label" use. Amiodarone premixed injection may be prescribed off-label to treat:
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