Heart Disease Home > Amiodarone Premixed Injection Side Effects

In clinical studies, amiodarone premixed injection was reported to cause common side effects like low blood pressure, a slow heart rate, and nausea. Many of the reactions to this medication tend to be minor and easy to treat. However, immediate medical treatment is required for side effects such as blurred vision, skin rashes, and coughing up blood.

An Introduction to Side Effects of Amiodarone Premixed Injection

Just like any medicine, amiodarone premixed injection (Nexterone®) can cause side effects. However, not everyone who uses the medication will have problems. In fact, many people tolerate it quite well. If side effects do occur, in many cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
(This article covers many, but not all, of the possible side effects with amiodarone premixed injection. Your healthcare provider can discuss a more complete list with you.)

Serious Amiodarone Premixed Injection Side Effects

Some side effects of this drug are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Shortness of breath, wheezing, or other problems breathing
  • Coughing or spitting up blood
  • Vision problems, such as:
    • Blurred vision
    • Halos
    • Problems with peripheral vision
    • Eye discomfort or pain
  • Any skin rash, as amiodarone premixed injection has been reported to cause life-threatening skin rashes, including rashes known as Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN)
  • Irritation, pain, redness, warmth, or swelling at the injection site
  • Signs of thyroid problems, such as:
    • Weakness
    • Unexplained weight loss or weight gain
    • An intolerance to hot or cold temperatures
    • Thinning of your hair
    • Sweating
    • Changes in your menstrual period (for women)
    • Swelling in your neck
    • Tremors
    • Feelings of nervousness, restlessness, or irritability
    • Problems concentrating
  • A bluish-gray skin tone
  • A fast, slow, pounding, or irregular heartbeat
  • Dizziness, lightheadedness, or fainting
  • Swelling of the hands, arms, legs, ankles, or feet
  • Signs of liver problems, such as:
    • Yellowing of the skin or whites of the eyes (jaundice)
    • Dark urine
    • Upper-right abdominal (stomach) pain
    • Nausea and vomiting
    • Excessive tiredness
  • Unusual bleeding or bruising
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
List of references (click here):
Other Articles in This eMedTV Presentation




Related Channels

eMedTV Links
Copyright © 2006-2019 Clinaero, Inc.

eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.

This site complies with the HONcode standard for trustworthy health information:
verify here.