Heart Disease Home > Amiodarone Premixed Injection Side Effects

Common Side Effects

Amiodarone premixed injection has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people using the medication were carefully documented. As a result, it was possible to see what side effects occurred and how common they were.
In clinical studies, the most common side effects of amiodarone premixed injection included:
  • Low blood pressure (hypotension) -- in up to 20.2 percent of people
  • A slow heart rate (bradycardia) -- up to 6 percent
  • Nausea -- up to 4.2 percent
  • Abnormal liver function tests -- up to 4.2 percent
  • Cardiac arrest (when the heart stops beating) -- up to 3.5 percent
  • Fever -- up to 2.9 percent
  • Heart rhythm problems -- up to 2.9 percent
  • Congestive heart failure -- up to 2.2 percent.
Other common side effects, occurring in up to 2 percent of people, included:
  • Diarrhea
  • Vomiting
  • Increased liver enzymes
  • Abnormal kidney function
  • Lung problems
  • A serious skin rash known as Stevens-Johnson Syndrome (SJS)
  • A decrease of platelets in the blood, which could increase the risk for bleeding.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while using amiodarone premixed injection or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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