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Fenofibric Acid

How Does It Work?

Fenofibric acid belongs to a class of drugs known as fibric acid derivatives (also known as fibrates). It works by increasing the activity of an enzyme (lipoprotein lipase) that breaks down triglyceride-rich particles and increases their removal from the body. The medication can also decrease the amount of these particles that are made and released from the liver. Depending on the type of cholesterol problem you have, fenofibric acid may also:
 

Clinical Effects

In one group of clinical research studies, people taking fenofibric acid were able to:
 
  • Reduce triglyceride levels by 31 percent
  • Reduce LDL cholesterol by 5.1 percent
  • Reduce total cholesterol by 12.4 percent
  • Raise HDL cholesterol by 16.3 percent.
     
Studies have also shown that combining fenofibric acid with a statin can provide further benefit.
 

When and How Should I Take Fenofibric Acid?

Some general considerations for when and how to take the medication include:
 
  • This medication comes in the form of a delayed-release capsule. It is taken by mouth once daily.
     
  • You can take fenofibric acid with food or on an empty stomach.
     
  • You must swallow the capsules whole. Do not chew, crush, dissolve, or open the capsules.
     
  • Be sure to take fenofibric acid at the same time each day to keep an even level of the medication in the blood.
     
  • For fenofibric acid to work properly, you have to take it as prescribed. It will not work if you stop taking it.
     
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Fenofibric Acid Drug Information

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