Fenofibric Acid Dosage

The recommended starting dosage of fenofibric acid for the treatment of severely high triglycerides is 45 to 135 mg once daily. The usual dosage for most people with high cholesterol is 135 mg once a day. People with mild to moderate kidney disease (who also have high cholesterol) typically need to start with a lower dose, such as 45 mg once daily.

An Introduction to Fenofibric Acid Dosing

The dosage of fenofibric acid delayed-release (Trilipix or choline fenofibrate) that your healthcare provider recommends will vary, depending on a number of factors, including:
 
  • How you respond to fenofibric acid
  • Other medical conditions you may have
  • Other medications you may currently be taking.
     
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 

Dosage for High Cholesterol

The recommended dose of fenofibric acid for most people with high cholesterol is 135 mg once daily. For people with mild to moderate kidney disease, a lower starting dosage (fenofibric acid 45 mg once daily) is recommended. Fenofibric acid is not recommended for people with severe kidney disease.
 

Dosage for High Triglycerides

The recommended starting fenofibric acid dose for treating severely high triglycerides is 45 to 135 mg once daily. Your healthcare provider should check your cholesterol and triglyceride levels in four to eight weeks before adjusting your dosage as necessary.
 

General Information on Fenofibric Acid Dosing

Some considerations for people taking fenofibric acid include:
 
 
  • This medication comes in the form of a delayed-release capsule. It is taken by mouth once daily.
     
  • You can take fenofibric acid with food or on an empty stomach.
     
  • You must swallow the capsules whole. Do not chew, crush, dissolve, or open the capsules.
     
  • Be sure to take this medication at the same time each day to keep an even level of the medication in your blood.
     
  • For fenofibric acid to work properly, you have to take it as prescribed. Fenofibric acid will not work if you stop taking it.
     
  • Remember that lowering cholesterol begins with lifestyle changes (weight loss, low cholesterol diet, and exercise). If lifestyle changes do not lower cholesterol to a desirable level, cholesterol medications (such as fenofibric acid) may be necessary. However, even for those who are taking cholesterol medication, lifestyle changes are still important for maintaining a good cholesterol level.
     
  • If you are unsure about anything related to fenofibric acid or your dosage of fenofibric acid, talk to your doctor, nurse, or pharmacist. Do not stop taking it without first discussing it with your healthcare provider.
     
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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