Effient Drug Interactions

Ibuprofen, warfarin, and celecoxib are just a few of the medications that can cause problems when taken with Effient. These drug interactions can increase your risk of internal bleeding, so it's important to have a discussion with your healthcare provider before taking Effient with any other medications.

Effient Medication Information

An Introduction to Interactions With Effient

Effient^® (prasugrel hydrochloride) can potentially interact with a few other medications. Some of the drugs that may lead to interactions with Effient include:

Antithrombin (ATryn^®, Thrombate III^®)
Argatroban
Aspirin (Bayer^® and others)
Bivalirudin (Angiomax^®)
Cilostazol (Pletal^®)
Clopidogrel (Plavix^®)
Dabigatran (Pradaxa^®)
Dipyridamole (Persantine^®)
Drotrecogin alfa (Xigris^®)
Eptifibatide (Integrilin^®)
Fondaparinux (Arixtra^®)
Heparin or heparin-like products, including dalteparin (Fragmin^®), enoxaparin (Lovenox^®), or tinzaparin (Innohep^®)
Lepirudin (Refludan^®)
Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:

Celecoxib (Celebrex^®)
Diclofenac (Cambia™, Cataflam^®, Flector^®, Pennsaid^®, Solaraze^® Gel, Voltaren^®, Voltaren^® Gel, Voltaren^®-XR, Voltaren Ophthalmic^®, Zipsor™)
Etodolac (Lodine^®, Lodine^® XL)
Ibuprofen (Motrin^®, Advil^®, Nuprin^®)
Indomethacin (Indocin^®, Indocin SR^®)
Ketoprofen (Orudis^®, Actron^®, Oruvail^®)
Ketorolac (Sprix™, Toradol^®)
Meloxicam (Mobic^®)
Nabumetone (Relafen^®)
Naproxen (Naprosyn^®) or naproxen sodium (Aleve^®, Anaprox^®, Naprelan^®)
Oxaprozin (Daypro^®)
Piroxicam (Feldene^®)
Others (see List of NSAIDs for a more complete list of these medications)

Pentoxifylline (Trental^®)
Rivaroxaban (Xarelto^®)
Thrombolytics, such as:

Alteplase (Activase^®)
Reteplase (Retavase^®)
Streptokinase (Streptase^®)
Tenecteplase (TNKase^®)

Ticagrelor (Brilinta™)
Ticlopidine (Ticlid^®)
Tirofiban (Aggrastat^®)
Warfarin (Coumadin^®, Jantoven^®).

Effient Drug Interactions Article Continues on Next Page >