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Dofetilide Side Effects

Potentially life-threatening heart rhythm problems are possible with dofetilide. Seek immediate medical treatment if you develop an abnormal heartbeat, dizziness, or unexplained swelling. Some of the commonly reported side effects of dofetilide include nausea, headaches, and insomnia. To minimize complications, let your healthcare provider know immediately if you develop anything that doesn't seem right.

An Introduction to Side Effects of Dofetilide

Just like any medicine, dofetilide (Tikosyn®) can cause side effects, some of which can be quite serious. As a result, this medication is reserved for cases involving severe symptoms. However, many side effects are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible dofetilide side effects. Your healthcare provider can discuss a more complete list with you.)

Serious Dofetilide Side Effects

Some side effects of dofetilide are potentially serious and should be reported immediately to your healthcare provider. These include but are not limited to:
  • Signs of an allergic reaction, such as:
    • An unexplained rash
    • Hives
    • Itching
    • Unexplained swelling, especially of the mouth, lips, or throat
    • Wheezing
    • Difficulty breathing or swallowing
  • An abnormal or fast heartbeat
  • Feeling faint or dizzy
  • Swelling of the arms, hands, legs, ankles, or feet
  • Loss of appetite
  • Sweating
  • Vomiting
  • Severe diarrhea
  • Increased thirst.
Because of the risk of life-threatening irregular heart rhythms with this medication, it can be started only in a hospital setting so that appropriate monitoring and emergency care can be provided. You will remain in the hospital for at least three days after beginning treatment.
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Dofetilide Medication Information

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