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When and How to Take This Medication

Some general considerations to keep in mind during treatment with dofetilide include the following:
  • Dofetilide comes in the form of a capsule. It is usually taken by mouth twice a day.
  • This medication must be started in a hospital setting so your heart rate and kidneys can be monitored. You will remain in the hospital for at least three days after beginning treatment.
  • You can take dofetilide with or without food. Try taking it with food if it seems to bother your stomach.
  • Try to take your doses at the same time each day to keep an even level of the drug in your bloodstream.
  • For dofetilide to work properly, it must be taken as prescribed.

Dosing Information for Dofetilide

The dose of dofetilide your healthcare provider recommends will vary, depending on a number of factors, including:
  • Your heart rate
  • Your kidney function
  • Other medical conditions you may have
  • Other medicines you are taking.
As is always the case, do not adjust your dosage unless your healthcare provider specifically tells you to do so.
(Click Dofetilide Dosage for more information.)

Drug Interactions

Dofetilide may react with a number of other medicines (see Drug Interactions With Dofetilide).

What If I Take an Overdose?

An overdose with this medication can be quite dangerous and could lead to a different, serious heart rhythm problem. If you take too much dofetilide, seek immediate medical attention.
(Click Tikosyn Overdose for more information.)
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Dofetilide Medication Information

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