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Important Information for Your Healthcare Provider

You should talk with your healthcare provider prior to taking this medication if you have:
  • Kidney disease, such as kidney failure (renal failure)
  • Liver disease, such as hepatitis, cirrhosis, or liver failure
  • A heart problem known as QT prolongation or long QT syndrome
  • Been told you have low blood potassium or low magnesium levels
  • Heart rhythm problems other than atrial fibrillation or atrial flutter
  • Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
(Click Precautions and Warnings With Dofetilide to learn more, including information on who should not take the drug.)

How Does Dofetilide Work?

Dofetilide belongs to a group of medications known as Class III antiarrhythmics. Class III antiarrhythmic medications block potassium channels in the heart, preventing potassium from leaving the heart muscle cells. This action extends the period of time that heart cells will not respond to a new electrical signal.
Atrial fibrillation or atrial flutter can occur when an electrical signal comes through too soon and prematurely activates heart tissue, leading to a rapid heart rate. By blocking potassium channels, dofetilide helps the heart tissue resist any premature electrical signal.
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Dofetilide Medication Information

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