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Side Effects of Dabigatran

Common Side Effects

In studies, dabigatran was compared to warfarin (Coumadin®, Jantoven®), the standard drug used for anticoagulation in people with atrial fibrillation. In these studies, the possible side effects of each medication were recorded and compared.
Up to 35 percent of people taking dabigatran experienced gastrointestinal problems, compared to 24 percent of people taking warfarin. These gastrointestinal problems included but were not limited to:
The other common side effect of dabigatran is bleeding. Bleeding side effects included:
  • Any bleeding -- in up to 16.6 percent of people taking dabigatran (compared to 18.4 percent with warfarin)
  • Major (serious) bleeding -- up to 3.3 percent (compared to 3.6 percent with warfarin)
  • Life-threatening bleeding -- up to 1.5 percent (compared to 1.9 percent with warfarin)
  • Bleeding in the brain -- up to 0.3 percent (compared to 0.8 percent with warfarin).

Final Thoughts

While dabigatran can be a life-saving drug, unfortunately the side effects can be life-threatening. Therefore, make sure to let your healthcare provider know if you develop any side effects while taking the drug or if something "just does not seem right." While it may not be related to the medication, your healthcare provider will be able to diagnose and treat the problem.
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Dabigatran Drug Information

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