CoQ10

Although the body naturally makes CoQ10, this vitamin-like substance may be low in some people who have certain medical conditions. As a result, these people may need to take a supplement. The supplements can cause nausea, diarrhea, and heartburn. CoQ10 is responsible for several functions within the cells of the body, such as producing an important energy molecule, protecting cells from damage, and stabilizing cellular membranes.

What Is CoQ10?

CoQ10 is short for coenzyme Q10 and is a vitamin-like substance necessary for life. Fortunately, the human body can make CoQ10 on its own, and most people probably do not need to take any supplements. However, levels can be low in people with certain medical conditions, and supplementation may be beneficial in some situations.
 
(Click Benefits of CoQ10 for more information on what this product is used for.)
 

How Does It Work?

CoQ10 has several different functions within the cells of the body, such as:
 
 
  • ATP production -- CoQ10 is important for the production of ATP, an important molecule in the body. ATP provides the energy for most of the processes within cells. The production of it occurs within certain structures in the cells known as mitochondria.
     
  • Antioxidant effects -- CoQ10 acts as an antioxidant, protecting cells from oxidation damage from free radicals. It also helps cells "recycle" other antioxidants, such as vitamins E and C.
     
  • Membrane stabilization -- CoQ10 may protect and stabilize cellular membranes.
     
These are just a few of the ways that researchers think the substance may work. As more studies are done, more information will become available about how it works.
 

Is CoQ10 Effective?

It's fairly clear that CoQ10 is not the universal cure-all or fountain of youth that it is sometimes claimed to be. However, research indicates that it seems to be effective for several different uses, although further research is necessary to confirm such findings (see Does CoQ10 Work?).
 

Dosing Information

Much more research is necessary before the safest and most effective dosage of CoQ10 can be determined. In addition, there is some speculation that different forms may be absorbed more easily than others.
 
(Click CoQ10 Dosage for more information.)
 

Side Effects of CoQ10

CoQ10 is usually tolerated quite well, although it can sometimes cause side effects, such as:
 
(Click CoQ10 Side Effects to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
 

Drug Interactions

CoQ10 can potentially interact with a few different medications (see CoQ10 Drug Interactions).
 

Safety Issues With CoQ10

Reasonable doses are probably safe for most people, especially if high-quality supplements are used, because these supplements are less likely to be contaminated or have other problems. Some people are more likely than others to experience problems. Therefore, you should talk with your healthcare provider prior to taking CoQ10 if you have:
 
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about any medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Is CoQ10 Safe? for more information, including any available warnings and precautions.)
 

What If I Take an Overdose?

It is not known what exactly to expect from an overdose, but it is reasonable to assume that taking too much may cause the usual side effects of CoQ10, but perhaps more severely.
 
(Click CoQ10 Overdose for more information.)
 

How Should CoQ10 Be Stored?

Refer to the label of your individual product for information on how best to store it. Keep CoQ10 and all medications and supplements out of the reach of children.
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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