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What Is Choline Fenofibrate Used For?

Unhealthy Cholesterol
High levels of cholesterol in the blood can accumulate on the walls of arteries (known as atherosclerosis or hardening of the arteries), leading to decreased blood flow and oxygen supply to the heart, brain, and other areas of the body. This can greatly increase a person's risk for developing conditions such as heart disease, angina (chest pain), a heart attack, and stroke.
 
Choline fenofibrate has been licensed for the treatment of high cholesterol in addition to a low-cholesterol diet and exercise. It works by lowering total cholesterol, LDL cholesterol, triglycerides, and ApoB (a component of cholesterol that is related to several heart disease risk factors). It can also raise HDL cholesterol, which is the good kind.
 
In general, cholesterol treatment is aimed at lowering LDL cholesterol levels enough to reduce the risk of developing complications associated with high cholesterol (see Effects of High Cholesterol). If you are at a higher risk, you will have a lower LDL goal.
 
(Click High Cholesterol Risk to see a list of factors that may affect your cholesterol level and a general guideline of ideal LDL cholesterol levels.)
 
High Triglycerides
High levels of triglycerides (fat-like substances in the body) in the blood can have many negative effects on the body. They can accumulate on the walls of arteries, which decreases blood flow and oxygen supply to the heart, brain, and other parts of your body. Hypertriglyceridemia can also increase a person's risk for developing heart disease, angina, a heart attack, and stroke.
 
Very high levels of this fat-like substance can produce a condition known as pancreatitis (inflammation of the pancreas). Pancreatitis can be quite painful, and sometimes causes serious health problems.
 
Choline fenofibrate has been licensed for the treatment of high triglycerides in addition to diet and exercise. It works by increasing the breakdown and removal of triglycerides so there are fewer in the body.
 
Like other similar medications, choline fenofibrate can actually cause an increase in LDL cholesterol (bad cholesterol) for people with very high levels of triglycerides (greater than 350 mg/dL). Therefore, choline fenofibrate should be used with caution in people with this condition who also have high levels of LDL cholesterol.
 
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Choline Fenofibrate Information

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