Cardizem Drug Interactions (Cont.)

Cardizem Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Cardizem is combined with any of the drugs listed above.
 
Benzodiazepines
Cardizem can increase the level of certain benzodiazepines in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your benzodiazepine dose to prevent this.
 
Beta Blockers
Combining Cardizem with a beta blocker may increase your risk of side effects, especially low blood pressure (hypotension) and slow heart rate (bradycardia). Your healthcare provider should closely monitor your heart rate and blood pressure if you are taking a beta blocker with Cardizem.
 
Buspirone (BuSpar)
Cardizem can increase the level of buspirone in your blood, potentially increasing your risk of side effects. Your healthcare provider may need to decrease your buspirone dosage as a result.
 
Carbamazepine (Tegretol, Tegretol XR)
Cardizem can increase the level of carbamazepine in your blood, possibly increasing your risk of side effects. Your healthcare provider may need to decrease your carbamazepine dosage to prevent this interaction from occurring.
 
Cimetidine (Tagamet)
Cimetidine may increase the level of Cardizem in your blood, increasing your risk of Cardizem side effects. Your healthcare provider may need to adjust your Cardizem dosage or suggest an alternative to cimetidine.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Cardizem may increase the level of cyclosporine in your blood, possibly increasing your risk of side effects. Your healthcare provider should monitor your cyclosporine levels and may need to adjust your dosage.
(Cardizem Drug Interactions Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;