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Cardene decreases blood pressure, reducing the risks that can occur with long-term high blood pressure (see Effects of High Blood Pressure). In clinical studies, it reduced systolic blood pressure by 16.3 mmHg and diastolic blood pressure by 15.4 mmHg, on average, in people with mild-to-moderate high blood pressure.
In people with exercise-induced angina (chronic stable angina), taking Cardene increased the amount of time they could exercise before chest pain occurred. It also decreased the frequency of chest pain.

When and How to Take Cardene

Some general considerations for when and how to take the medication include:
  • The medication comes in the form of a capsule. It is taken by mouth, usually three times a day.
  • It is best to take it on an empty stomach, such as before meals.
  • It should be taken at the same times each day to maintain an even level of the drug in your blood.
  • For the medication to work properly, it must be taken as prescribed. It will not work if you stop taking it.


The dose of Cardene your healthcare provider recommends will vary depending on a number of factors, including:
  • The medical condition being treated
  • Other medical conditions you may have
  • Other medications you may currently be taking.
As is always the case, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
(Click Cardene Dosage for more information.)
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Cardene Drug Information

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