Cardene Drug Interactions

When cimetidine or cyclosporine is taken together with Cardene, drug interactions may occur. These interactions with Cardene can alter the amounts of the medications in your blood, increasing your risk of side effects. Your healthcare provider may need to adjust your Cardene dose or may suggest another medication. Prior to taking Cardene, make sure to talk to your healthcare provider about possible drug interactions that may apply to you.

 

An Overview of Cardene Drug Interactions

Cardene® (nicardipine hydrochloride) can potentially interact with a few other medicines. Some of these medicines that may lead to Cardene drug interactions include:
 

Cardene Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Cardene is combined with any of the drugs listed above.
 
Cimetidine (Tagamet)
Cimetidine may increase the level of Cardene in your blood, increasing your risk of Cardene side effects. Your healthcare provider may need to adjust your Cardene dose or may suggest an alternative to cimetidine.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Taking cyclosporine with Cardene can increase the level of cyclosporine in your blood, increasing your risk of side effects. Your healthcare provider should carefully monitor the level of cyclosporine in you blood, adjusting your dose as necessary.
 

Final Thoughts on Cardene Drug Interactions

It is possible that not every Cardene drug interaction was discussed in this article.
 Therefore, you should talk with your pharmacist or healthcare provider about drug interactions with Cardene that may apply to your situation.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;