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Cardene and Depression

Some people may experience side effects during treatment with Cardene, and depression appears to be one of these possible side effects. In clinical studies, depression was reported in less than 1 percent of people using the medication. However, because depression is so common within the general population, it is difficult to determine whether depression is actually caused by the drug, other factors, or a combination of both.

Cardene and Depression: An Overview

Cardene® (nicardipine hydrochloride) is a prescription medication known as a calcium channel blocker. It is used to treat chest pain (known medically as angina) and high blood pressure (hypertension). A long-acting version (Cardene SR®) is also available and is approved to treat high blood pressure.
As with any medication, there are potential side effects with Cardene. One of these possible side effects is depression.

Cardene and Depression: How Common Is It?

The safety and effectiveness of Cardene has been studied in many people. In these clinical trials, less than 1 percent of people reported depression as a side effect of Cardene.
The challenge with Cardene and depression is that, given how rarely depression is reported with Cardene and how common it is within the general population, it is difficult to tell whether depression is caused by Cardene, other factors, or a combination of both.

Cardene and Depression: Recommendations

For people taking Cardene, depression may occur. Therefore, if you notice any possible symptoms of depression while taking Cardene, or something "just does not seem right," you should talk to your healthcare provider. He or she will be able to diagnose and treat the problem. If your healthcare provider believes the medicine may be causing your symptoms, he or she may recommend another angina or blood pressure medicine.
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