Combining Betapace with digoxin may cause a dangerously slow heart rate (bradycardia) or new or worsened arrhythmias. You may need to be monitored closely if you take these medications together. In some cases, Betapace and digoxin should not be combined.
Many Asthma or COPD Medications
As a beta blocker, Betapace may interfere with the effectiveness of many asthma or COPD medications. This is usually not an issue, since people with asthma or COPD should not take Betapace anyway (it can worsen breathing problems). In the rare case that a healthcare provider recommends that such medications be taken together, higher-than-normal doses of the asthma or COPD medications may be required.
Other Beta Blockers
Betapace is a beta blocker and generally should not be combined with other beta blockers, as this may increase the risk of serious side effects.
Betapace can cause a dangerous change in the heart rhythm known as QT prolongation. To help decrease the risk of this problem, it should not be combined with other drugs that have this effect. Many different types of medications can cause this (see QT-Prolonging Medications for a list of such medications).
Combining reserpine with a beta blocker can increase the risk of serious side effects. You may need to be monitored closely if you take these medications together. In some cases, Betapace should not be combined with reserpine.
It is possible that not all interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about any specific Betapace drug interactions that may apply to you.