Betapace Drug Interactions Explained
The following sections explain in detail the potentially negative interactions that can occur when Betapace is combined with any of the drugs listed above.
Do not take antacids that contain aluminum hydroxide or magnesium hydroxide within two hours of taking Betapace, as this may decrease the level of Betapace in the blood.
Calcium Channel Blockers
Combining Betapace with certain calcium channel blockers may cause a dangerously low blood pressure (hypotension), a slow heart rate (bradycardia), and heart failure. You may need to be monitored closely if you take these medications together. In some cases, Betapace and a calcium channel blocker should not be combined.
Some diuretics may cause low electrolytes (such as low potassium levels), which may increase the risk of dangerous arrhythmias due to Betapace. If you take Betapace with such diuretics, your electrolytes will need to be carefully monitored.
Certain Other Arrhythmia Medications
Certain other arrhythmia medications should not be combined with Betapace, as this may have negative effects on the heart rhythm.
If you take both clonidine and Betapace, stopping clonidine without stopping Betapace could increase the risk of dangerously high blood pressure, strokes, and other serious problems. People are generally advised to stop taking Betapace several days before gradually reducing the dose of clonidine. Do not attempt this, however, without the approval and supervision of your healthcare provider.
Betapace may increase blood sugar, and your healthcare provider may need to adjust the dosage of your diabetes medications. Also, Betapace could mask some of the signs of low blood sugar, especially a racing heart; this could be dangerous for people who are prone to low blood sugar episodes.