Potential problems with amlodipine besylate (Norvasc®) should be reviewed with your healthcare provider before beginning treatment for a condition affecting the cardiovascular system. For example, if you have congestive heart failure or liver disease, make sure to let your healthcare provider know before you start taking amlodipine. If you have liver disease or liver failure, as your body may not metabolize the medication as well as it should. In general, calcium channel blockers such as amlodipine should not be used in people with congestive heart failure.
This medicine may cause a number of side effects. Some of the most common amlodipine problems that were reported in clinical trials included drowsiness, fatigue, flushing, and swelling or water retention. Some of the less common but potentially serious side effects that should be reported to your healthcare provider immediately include irregular heart rhythm, rapid weight gain, and high blood sugar.
(Click Amlodipine Side Effects and Precautions and Warnings of Amlodipine to find out what else you should discuss with your healthcare provider before using this drug and a more complete list of possible problems.)